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Helps reduce gingivitis, periodontitis, peri-mucositis and peri-implantitis

PerioTabs® is a unique and easy to use brushing solution for gums, teeth and dental implants to help reduce gingivitis, periodontitis, peri-mucositis and peri-implantitis through elimination of dental biofilm accumulation. The procedure is easy, safe to use and consists of brushing gums, teeth and dental implants with small effervescent tablets that dissolve in lukewarm water.

The formulation of PerioTabs® is based on the unique NitrAdine® anti-biofilm tablet formula, that results in a highly active solution. When dissolved in lukewarm water, the solution removes pathogenic biofilm from gums, teeth and dental implants to clinically insignificant levels. The mode of action of NitrAdine’s® efficacy is based on the combination of a high concentration of surfactant (SLS) and other ingredients. The surfactant denatures the biofilm/micro-organism membrane proteins, whilst the other ingredients result in a slow release of a non-toxic concentration of only 0.02% hypochlorite, killing all micro-organisms (bacteria, fungi and viruses) present within the biofilm. (NitrAdine® is not hypochlorite. Hypochlorite (bleach), is a 2-10% concentration of NaOCI, which is toxic and cannot be used in the mouth).

Several independent academic in-vitro studies have demonstrated that NitrAdine® induces a significant reduction of biofilm formed by Candida albicans, Staphylococcus aureus, Streptococcus mutans and Pseudomonas aeruginosa on oral medical devices. In addition, an anti-viral activity against Herpes simplex was observed. Recent clinical studies in patients suffering from chronic periodontitis demonstrated that brushing with PerioTabs® solution for 10 days, induces a significant reduction of periodontopathogenic bacteria including Porphyromonas gingivalis, Provotella intermedia and Aggregatibacter actinomycetemcomitans. NitrAdine® also reduces micro-organisms present on toothbrush heads.

Additional properties of NitrAdine®:

  • Non-toxic to gums (non-irritating, non-sensitizing)
  • Non-antibiotic
  • Reduces micro-organisms present on toothbrush heads
  • Compatible with all toothbrush heads

For more production information register your interest through the contact page.


What is PerioTabs®?

PerioTabs® helps reduce gingivitis, periodontitis, peri-mucositis and peri-implantitis through elimination of oral biofilm accumulation on gums, teeth and dental implants and is to be used only if recommended by the dentist. The procedure consists of brushing the teeth and gums with the provided tablets dissolved in lukewarm water (Figure 1).

The formulation of PerioTabs® is based on the NitrAdine® anti-biofilm formula and is intended for use in the oral cavity on gums and teeth.

PerioTabs® contains 10 small effervescent tablets (1 tablet per day for 10 days). One tablet is to be dissolved in 15 ml of lukewarm water in the provided container. Whilst the tablet is dissolving, the toothbrush should be immersed in the solution and left for 15 minutes. This will allow the toothbrush bristles to absorb the PerioTabs® solution (Figure 2) before brushing commences. The patient should then brush their teeth and gums with the solution for 2 minutes (Figure 3). This process should be repeated for 10 consecutive days.

PerioTabs® is a Medical Device Class I product, and patent pending in Europe and USA (application numbers EP15798353.7 and US 15/526,247).

PerioTabs® clinical results

A clinical trial was conducted on 20 chronic periodontal patients after scaling and root planing (SRP) and the PerioTabs® treatment, which consisted of 10 days brushing the gums and teeth,
resulted in a significant reduction of:

  • Plaque index
  • Gingival index
  • Bleeding
  • Halitosis