R & D

R & D

bonyf extends its portfolio of innovative products through commitment to substantially invest in the high added value product development to address the growing demands of denture wearers, gum irritation treatments and skin care with a focus on wound healing applications; for both the professionals and consumers.

Short term R&D at bonyf is focusing on the following developments:

  • A NitrAdine® based antibiofilm long lasting adhesive paste to prevent cross contamination in the final stages of the implant procedure, targeted to dental professionals;
  • An organic olive oil adhesive cream containing NitrAdine® to prevent denture stomatitis;
  • A topical formulation for the treatment of skin and foot ulcers in diabetic patients;
  • A NitrAdine® based antibiofilm formulation for gingival pocket disinfection, targeted to dental professionals; and
  • A NitrAdine® based toothpaste.

Short term R&D at bonyf is focusing on the following developments:

  • A NitrAdine® based antibiofilm long lasting adhesive paste to prevent cross contamination in the final stages of the implant procedure, targeted to dental professionals;
  • An organic olive oil adhesive cream containing NitrAdine® to prevent denture stomatitis;
  • A topical formulation for the treatment of skin and foot ulcers in diabetic patients;
  • A NitrAdine® based antibiofilm formulation for gingival pocket disinfection, targeted to dental professionals; and
  • A NitrAdine® based toothpaste.

PRECLINICAL/CLINICAL

bonyf is committed to scientific validation of its products and is actively engaged in preclinical and clinical research programs, collaborating with leading centres of excellence, in both gum infection diseases and dental care globally. There are currently over 20 on-going studies with key opinion leaders in 12 countries.

PUBLICATIONS

Listed below are scientific publications demonstrating the efficacy and safety of bonyf’s products. The papers are written by recognized scientists in academic institutions and research laboratories. Copies are available on request.

PRECLINICAL/CLINICAL

bonyf is committed to scientific validation of its products and is actively engaged in preclinical and clinical research programs, collaborating with leading centres of excellence, in both gum infection diseases and dental care globally. There are currently over 20 on-going studies with key opinion leaders in 12 countries.

PUBLICATIONS

Listed below are scientific publications demonstrating the efficacy and safety of bonyf’s products. The papers are written by recognized scientists in academic institutions and research laboratories. Copies are available on request.

Our Recent Publications

Timeline

2019
February 16

Mascolo A., et al. (2019). Clinical and patient satisfaction evaluation of an organic olive oil-based denture adhesive cream, OlivaFix Gold®, in denture wearers from 3 European countries with different socio-economical Characteristics. EC Dental Science 18.9, 2196-2205.

2017
May 13

Sakly A., Jutla Y., Jutla B., Hadded I., De Wever B., Satia M., and Bogaert J.P. (2017). Clinical and microbiological effects of PerioCream a periodontal dressing combined with an antimicrobial gum brushing solution after scaling and root planing: A multi-center randomized clinical trial. J Dent Oral Care 2, 1–6.

2016
November 4

Sakly A., De Wever B., Jutla B., Satia M., Bogaert JP. (2016). The safety and efficacy of AphtoFix® mouth ulcer cream in the management of recurrent aphthous stomatitis. BMC Oral Health 11, 16-17.

November 4

Coimbra F.C.T., Salles M.M., De Oliveira V.C., Macedo A.P., Da Silva C.H.L., Pagnano V.O., and Paranhos H. de F.O. (2016). Antimicrobial efficacy of complete denture cleansers. Am. J. Dent. 29, 149–153.

November 4

Darwish M., and Nassani M. (2016). Evaluation of the effect of denture adhesives on surface roughness of two chemically different denture base resins. Eur. J. Dent. 10, 321.

2015
July 25

Fathi H., Martiny H., Jost-Brinkmann P-G., (2015). Efficacy of cleaning tablets for removable orthodontic appliances. J. Orofac. Orthop. / Fortschritte der Kieferorthopädie 76, 143–151.

2012
February 2

Decelis S., Camilleri S., Zahra E.V., Scerri E., and De Wever B. (2012). The effect of NitrAdine® on the Candida levels of maxillary removable appliances. Quintessence Int. 43, 239–245.

2011
July 4

Glass R.T., Conrad R.S., Köhler G.A., Warren A.J., and Bullard J.W. (2011). Microbiota found in protective athletic mouthguards. Sports Health 3, 244–248.

July 4

Vento-Zahra E., De Wever B., Decelis S., Mallia K., and Camilleri S. (2011). Randomized, double-blind, placebo-controlled trial to test the efficacy of NitrAdine® tablets in maxillary removable orthodontic appliance patients. Quintessence Int. 42, 37–43.

2010
July 5

Silva-Lovato C.H., De Wever B., Adriaens E., Paranhos H., Watanabe E., Pisani M.X., Souza R.F. de, and ItoI. Y. (2010). Clinical and antimicrobial efficacy of NitrAdine®-based disinfecting cleaning tablets in complete denture wearers. J. Appl. Oral Sci. 18, 560–565.

2008
October 28

Coenye T., De Prijck K., De Wever B., and Nelis H.J. (2008). Use of the modified Robbins device to study the in vitro biofilm removal efficacy of NitrAdine®, a novel disinfecting formula for the maintenance of oral medical devices. J. Appl. Microbiol. 105, 733–740.

2004
October 28

Glass RT., Bullard JW., Conrad RS., Blewett EL. (2004). Evaluation of the sanitization effectiveness of a denture-cleaning product on dentures contaminated with known microbial flora. An in vitro study. Quintessence Int. 35, 194–199.